Method Development Strategies to Exploit Selectivity

Introduction

(U)HPLC Method Development Strategies to Exploit Selectivity
In this seminar, we review the importance of chromatographic selectivity from a theoretical and practical perspective and how this relates to analyte resolution for method development. With an understanding of selectivity and using a variety of chromatographic data, we discuss phase design principles and how it is possible to introduce functionality that enhances selectivity, whilst maximising other desirable phase attributes such as phase stability, reproducibility and mechanisms of interaction. The resulting novel phases are explored for their improved chromatographic performance, selectivity and value in method development for a range of analytes and separations. Finally, method development approaches are discussed and pragmatic, simple method development platforms are illustrated based upon rational phase and eluent choice.

Chromatographic selectivity
Stationary phase design
HPLC & UHPLC
Examples
Alternative phases
Conclusions

Available as in-house or off-site courses. Contact us for details
Tel: 0118 930 3660 Email: seminars@hichrom.co.uk

Deadlines

Apr 13 2016
Standard registration deadline

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Speakers

Venue

Bristol Marriott City Centre

Wallace Suite, Bristol Marriott City Centre, 2 Lower Castle Street, Old Market, Bristol, BS1 3AD, United Kingdom

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Hichrom is one of the world’s leading HPLC column manufacturers and has been firmly established in the field of Liquid Chromatography for over 30 years, developing, manufacturing and supplying the highest quality LC columns throughout the world. During this time Hichrom has built up a strong reputation amongst chromatographers for our technical expertise. Our speakers are experienced chromatographers who will be happy to discuss your questions on a wide variety of HPLC/UHPLC topics including: troubleshooting, method development, reproducibility, batch reservation, custom packing/bonding, application support, method transfer & column selection.

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