A new generation of molecules is being developed to leverage the cellular machinery to disrupt protein-protein interactions (PPI), induce proximity, and seek out previously 鈥渦ndruggable鈥 targets for therapeutic intervention. Cambridge Healthtech Institute鈥檚 symposium, focused on Covalent Chemistries and Induced Proximity, brings together experts to discuss innovative science and novel techniques that are driving new thinking in drug discovery and diversifying treatment options. This symposium is a part CHI's 22nd Annual Discovery on Target.