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°ÄÃÅÁùºÏ²Ê¿ª½±¼Ç¼ Desktop Seminars with Brazilian Chemical Society Organic Chemistry Division (18 Aug)

18 August 2020 11:30-13:00, Brazil


Introduction
°ÄÃÅÁùºÏ²Ê¿ª½±¼Ç¼ Desktop Seminars in Organic Chemistry with the Brazilian Chemical Society 2020 are an initiative from the °ÄÃÅÁùºÏ²Ê¿ª½±¼Ç¼ and the Brazilian Chemical Society to bring cutting-edge research directly to you!

Covid-19 has exposed us to a new reality where the virtual world is much more important than before. In order to keep our students engaged at the frontiers of Organic Chemistry, we have organized a weekly webinar series that is a joint collaboration between the °ÄÃÅÁùºÏ²Ê¿ª½±¼Ç¼ (°ÄÃÅÁùºÏ²Ê¿ª½±¼Ç¼) and the Organic Chemistry Division of the Brazilian Chemical Society (SBQ). It is an alternative way to share work and interact with potential collaborators.

The sections will alternate between Brazilian and international speakers, in some cases with the opportunity for a selected Brazilian early career researcher to engage with the audience by presenting their recent independent career developments.

Programme

11:30 Introductions and welcome
11:35 Early Career presentation with Q&A
11:50 Main Presentation with Q&A
12:45 Closing remarks
13:00 Close

Speakers

Professor Luiz Carlos Dias
Drug discovery for the most neglected

In March 2013 we initiated a collaboration with DNDi (Drugs for Neglected Diseases initiative, www.dndi.org), a nonprofit organization, designated LOLA (Lead Optimization Latin America).  LOLA´s mission is to discover and develop new drugs for the treatment of parasitic tropical diseases with an emphasis on Chagas disease and visceral leishmaniasis. At the same time, we initiated a collaboration with MMV (Medicines for Malaria Venture, www.mmv.org), also a nonprofit organization, designated Brazil Heterocycles. With MMV, we are looking for an oral drug to cure a patient of malaria, but as an extra challenge, we are working to develop a ONE DOSE treatment. A key element of these projects is to discover compounds that could ultimately be used for the prevention and treatment of malaria, Chagas disease and visceral leishmaniasis. These collaborations with both DNDi and MMV are unprecedented in Brazil and will help to advance drug discovery of poverty-related diseases endemic to the country.

Prof. Dr. Taícia Pacheco Fill
The chemistry hidden in the biological interactions found in the citrus host

Phytopathogens have developed a variety of specialized virulence strategies to facilitate colonization of plant tissue, and successfully infect and modulate the host plant physiology, including the production of low-molecular-weight phytotoxins (secondary metabolites). Brazil is the world's largest producer of citrus, which are susceptible to a number of diseases that cause significant losses during the postharvest phase. The most common and serious diseases that affect citrus are green and blue molds caused, respectively, by Penicillium digitatum andPenicillium italicum. The actual research concerning such pathogens focuses on treatments against the infection symptoms. However, the molecular basis of infection and specificity towards the host remain largely unknown. In this sense, in our projects we try to elucidate the biologically active constituents of host-pathogen interaction and study them concerning functionality.  The interactions between citrus phytopathogens are also investigated in our laboratory trying to search for new and safer antifungal compounds.


 
Speakers
Professor Luiz Carlos Dias, University of Campinas-UNICAMP, Brazil

Luiz Dias was born in Balneário Camboriú, SC (Brazil). He received his undergraduate degree from the Federal University of Santa Catarina (UFSC), in 1988. He received his PhD, in 1993 at the University of Campinas (UNICAMP). He spent two years as a postdoctoral fellow with Prof. David A. Evans at Harvard University, USA (1994–1995). In 1992 he joined the faculty at the Institute of Chemistry at UNICAMP and in 2008 he was promoted to Full Professor. He is interested in total synthesis of biologically active natural products and is involved with DNDi and MMV in the synthesis of potential candidates for the treatment of Chagas Disease, leishmaniasis and malaria. Prof. Dias has about 115 publications and has delivered more than 200 Lectures. Luiz Dias is a Researcher level 1A of CNPq. In 1999, Prof. Dias received the Zeferino Vaz Award for excellence in teaching and research activities at UNICAMP, in 2010 he was elected Commander of the National Order of Scientific Merit (Presidency). In 2011 he was elected Full Member of the National Academy of Sciences (ABC), and in 2014 he became Fellow of the °ÄÃÅÁùºÏ²Ê¿ª½±¼Ç¼ (°ÄÃÅÁùºÏ²Ê¿ª½±¼Ç¼) and Fellow of IUPAC. In 2015, Prof. Dias was honoured in the initiative "175 Faces of Chemistry", °ÄÃÅÁùºÏ²Ê¿ª½±¼Ç¼ and received the Simão Mathias Medal from the Brazilian Chemical Society.


Prof. Dr. Taícia Pacheco Fill, University of Campinas - UNICAMP, Brazil

Taícia received her PhD at the Universidade Federal de São Carlos in 2014 under the supervision of Prof. Dr. Edson Rodrigues Filho, with a one year internship at the University of Cambridge in the laboratory of Prof. Dr. Peter Leadlay. In 2015 she became a MS-3 professor at the Institute for organic chemistry at the institute of UNICAMP and in 2016 she joined the group of Prof. Dr. Christian Hertweck at the Leibniz Institute for Natural Product Research and Infection Biology as a postdoctoral fellow, which she returned in 2018 and 2020 as a visiting professor. She coordinates the Microbial Chemical Biology laboratory which is funded by FAPESP, the Alexander von Humboldt Foundation and the Serrapilheira Institute (grantee 2020). In 2019, she was the winner in the chemical sciences category of the For Women in Science award granted by LOreal-UNESCO-ABC. She has experience in Organic Chemistry, with emphasis on the chemistry of microbial natural products, working mainly in chemical ecology, pathogen-host interactions, biosynthesis of fungal secondary metabolites, molecular biology, genetic manipulation and expression of microbial enzymes in the understanding of biosynthetic mechanisms.



Venue
Go To Webinar

Go To Webinar, Brazil

Organised by
°ÄÃÅÁùºÏ²Ê¿ª½±¼Ç¼ and the Sociedade Brasileira de Química
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